The Fountain (2006)

Darren Aronofsky directs this elegaic time-travelling odyssey, in which Hugh Jackman and Rachel Weisz star in a series of storylines about a man’s struggle to save the woman he loves. In one storyline, 16th-century Spanish conquistador Tomas Creo (Jackman) sets out to find the fabled Tree of Life in order to save his queen, Isabel (Weisz) from the Inquisition. In a modern-day storyline, Jackman is Tommy, a scientist desperately searching for the medical breakthrough that will save the life of his cancer-stricken wife, Izzie (Weisz). In a future timeline, Tom (Jackman) is a 26th-century astronaut travelling through deep space – and finally beginning to grasp the mysteries of life that have consumed him for so long.